Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
baiABile acid 7-dehydroxylase 1/3; KEGG: cpf:CPF_1154 2.4e-66 7-alpha-hydroxysteroid dehydrogenase K00076; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: Cytoplasmic, score: 9.98. (248 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.728
EDR45496.1
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 
 0.652
EDR48434.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: btl:BALH_0703 2.0e-140 ndh; NADH dehydrogenase K00356; COG: COG0607 Rhodanese-related sulfurtransferase; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.610
fabD
[acyl-carrier-protein] S-malonyltransferase; KEGG: cac:CAC3575 2.9e-77 fabD; malonyl CoA-acyl carrier protein transacylase K00645; COG: COG0331 (acyl-carrier-protein) S-malonyltransferase; Psort location: Cytoplasmic, score: 8.87.
 
 0.573
fabF
Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.568
trxA
Thioredoxin; KEGG: mbo:Mb3945 4.1e-23 trxC; thioredoxin TrxC (TRX) (MPT46) K03671; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score: 9.65; Belongs to the thioredoxin family.
  
   0.567
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
    
   0.553
EDR46260.1
Hypothetical protein; KEGG: gox:GOX1019 1.6e-06 putative exonuclease K01146; COG: COG0420 DNA repair exonuclease; Psort location: Cytoplasmic, score: 8.87.
    
   0.553
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
  
 0.542
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.524
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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