STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR48452.1COG: COG3943 Virulence protein; Psort location: Cytoplasmic, score: 8.87. (336 aa)    
Predicted Functional Partners:
EDR46670.1
Hypothetical protein.
  
    0.651
EDR48451.1
Ser/Thr phosphatase family protein; COG: COG4186 Predicted phosphoesterase or phosphohydrolase; Psort location: Cytoplasmic, score: 8.87.
       0.491
EDR47422.1
Hypothetical protein; COG: COG4804 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
 
     0.486
EDR48453.1
Hypothetical protein; COG: COG3547 Transposase and inactivated derivatives; Psort location: Cytoplasmic, score: 8.87.
       0.480
EDR48454.1
Hypothetical protein; KEGG: bcc:BCc_281 0.0089 recC; RecC K01144; Psort location: CytoplasmicMembrane, score: 9.99.
       0.430
EDR48343.1
Hypothetical protein; COG: COG4804 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
 
     0.427
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.401
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.