STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR48333.12-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family; KEGG: cno:NT01CX_0146 4.8e-22 porD; pyruvate synthase subunit PorD K00168; COG: COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit; Psort location: Cytoplasmic, score: 8.87. (100 aa)    
Predicted Functional Partners:
EDR48334.1
Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; KEGG: ctc:CTC02526 2.0e-126 porA; pyruvate synthase subunit porA K00169; COG: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Psort location: Cytoplasmic, score: 8.87.
 
 0.999
EDR48335.1
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein; KEGG: ctc:CTC02525 4.2e-101 porB; pyruvate synthase subunit porB K00170; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
 
 0.999
nifJ
KEGG: ctc:CTC01741 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 0.999
EDR48332.1
2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family; KEGG: cno:NT01CX_0147 5.6e-67 porG; pyruvate synthase subunit PorC K00168; COG: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.994
EDR46533.1
4Fe-4S binding domain protein; KEGG: chy:CHY_0732 2.8e-200 hydB; Fe-hydrogenase, beta subunit K00335; COG: COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; Psort location: Cytoplasmic, score: 9.98.
    
 0.897
EDR47352.1
Aldehyde dehydrogenase (NAD) family protein; KEGG: cpe:CPE2531 0. adhE; alcohol dehydrogenase / acetaldehyde dehydrogenase K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
    
 0.890
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
     
 0.876
ppdK
Pyruvate, phosphate dikinase; KEGG: tte:TTE0981 0. ppsA2; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01006; COG: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Psort location: Cytoplasmic, score: 9.98; Belongs to the PEP-utilizing enzyme family.
    
 0.872
EDR48336.1
Propanediol utilization protein PduL; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.
    
  0.870
fsa
Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
     
 0.861
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.