STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ligADNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (647 aa)    
Predicted Functional Partners:
nifJ
KEGG: ctc:CTC01741 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
   
   0.904
leuS
leucine--tRNA ligase; KEGG: bld:BLi03175 1.4e-237 leuS; leucyl-tRNA synthetase; RBL03411 K01869; COG: COG0495 Leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.98; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 
 0.831
EDR48387.1
KEGG: cpe:CPE2313 4.8e-61 pseudouridylate synthase K06182; COG: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Psort location: Cytoplasmic, score: 8.87; Belongs to the pseudouridine synthase RsuA family.
       0.792
sun
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.778
clpX
KEGG: bcz:BCZK4216 2.8e-97 clpX; ATP-dependent Clp protease, ATP-binding subunit K03544; COG: COG1219 ATP-dependent protease Clp, ATPase subunit; Psort location: Cytoplasmic, score: 8.87.
       0.725
pcrA
KEGG: efa:EF0721 4.4e-186 pcrA; ATP-dependent DNA helicase PcrA K03657; COG: COG0210 Superfamily I DNA and RNA helicases; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.716
EDR48385.1
Putative phage shock protein B; KEGG: cal:orf19.2859 6.8e-09 SRP40; nonribosomal protein of the nucleolus and coiled bodies K01186; COG: COG5295 Autotransporter adhesin; Psort location: Cellwall, score: 9.93.
  
    0.696
EDR48386.1
MBOAT family protein; KEGG: pen:PSEEN4543 8.9e-49 algI; alginate O-acetylation protein AlgI K00680; COG: COG1696 Predicted membrane protein involved in D-alanine export; Psort location: CytoplasmicMembrane, score: 9.99.
       0.686
EDR47983.1
UvrD/REP helicase; KEGG: cac:CAC1003 6.9e-91 superfamily I DNA helicase (rep-like helicase) K01529; COG: COG0210 Superfamily I DNA and RNA helicases; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.673
EDR48392.1
Hypothetical protein; This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
 
   
 0.644
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.