| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDR46210.1 | EDR48249.1 | DORFOR_02818 | DORFOR_00374 | Methyltransferase domain protein; KEGG: ctc:CTC00225 1.7e-51 methyltransferase K00599; COG: COG4123 Predicted O-methyltransferase; Psort location: Cytoplasmic, score: 8.87; Belongs to the methyltransferase superfamily. | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.580 |
| EDR46210.1 | tmcAL | DORFOR_02818 | DORFOR_01465 | Methyltransferase domain protein; KEGG: ctc:CTC00225 1.7e-51 methyltransferase K00599; COG: COG4123 Predicted O-methyltransferase; Psort location: Cytoplasmic, score: 8.87; Belongs to the methyltransferase superfamily. | Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. | 0.715 |
| EDR47970.1 | EDR48243.1 | DORFOR_00627 | DORFOR_00368 | Hypothetical protein; COG: COG2384 Predicted SAM-dependent methyltransferase; Psort location: Cytoplasmic, score: 8.87. | COG: COG4481 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | 0.701 |
| EDR47970.1 | EDR48249.1 | DORFOR_00627 | DORFOR_00374 | Hypothetical protein; COG: COG2384 Predicted SAM-dependent methyltransferase; Psort location: Cytoplasmic, score: 8.87. | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.557 |
| EDR47970.1 | polC | DORFOR_00627 | DORFOR_02444 | Hypothetical protein; COG: COG2384 Predicted SAM-dependent methyltransferase; Psort location: Cytoplasmic, score: 8.87. | DNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.635 |
| EDR48243.1 | EDR47970.1 | DORFOR_00368 | DORFOR_00627 | COG: COG4481 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; COG: COG2384 Predicted SAM-dependent methyltransferase; Psort location: Cytoplasmic, score: 8.87. | 0.701 |
| EDR48243.1 | EDR48249.1 | DORFOR_00368 | DORFOR_00374 | COG: COG4481 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.604 |
| EDR48243.1 | polC | DORFOR_00368 | DORFOR_02444 | COG: COG4481 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | DNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.400 |
| EDR48249.1 | EDR46210.1 | DORFOR_00374 | DORFOR_02818 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Methyltransferase domain protein; KEGG: ctc:CTC00225 1.7e-51 methyltransferase K00599; COG: COG4123 Predicted O-methyltransferase; Psort location: Cytoplasmic, score: 8.87; Belongs to the methyltransferase superfamily. | 0.580 |
| EDR48249.1 | EDR47970.1 | DORFOR_00374 | DORFOR_00627 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Hypothetical protein; COG: COG2384 Predicted SAM-dependent methyltransferase; Psort location: Cytoplasmic, score: 8.87. | 0.557 |
| EDR48249.1 | EDR48243.1 | DORFOR_00374 | DORFOR_00368 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | COG: COG4481 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | 0.604 |
| EDR48249.1 | EDR48463.1 | DORFOR_00374 | DORFOR_00205 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | YbbR-like protein; COG: COG4856 Uncharacterized protein conserved in bacteria. | 0.616 |
| EDR48249.1 | dnaB | DORFOR_00374 | DORFOR_00376 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.830 |
| EDR48249.1 | ecfT | DORFOR_00374 | DORFOR_03277 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Cobalt transport protein; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | 0.532 |
| EDR48249.1 | galE | DORFOR_00374 | DORFOR_00373 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | KEGG: bsu:BG11837 4.9e-123 galE; UDP-glucose 4-epimerase K01784; COG: COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | 0.773 |
| EDR48249.1 | polC | DORFOR_00374 | DORFOR_02444 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | DNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.612 |
| EDR48249.1 | rplI | DORFOR_00374 | DORFOR_00375 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Ribosomal protein L9; Binds to the 23S rRNA. | 0.927 |
| EDR48249.1 | tmcAL | DORFOR_00374 | DORFOR_01465 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. | 0.588 |
| EDR48463.1 | EDR48249.1 | DORFOR_00205 | DORFOR_00374 | YbbR-like protein; COG: COG4856 Uncharacterized protein conserved in bacteria. | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.616 |
| dnaB | EDR48249.1 | DORFOR_00376 | DORFOR_00374 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.830 |