Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (446 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 0.915
rplI
Ribosomal protein L9; Binds to the 23S rRNA.
  
  
 0.856
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 
 0.852
EDR48249.1
DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
    0.811
EDR48161.1
Hypothetical protein; KEGG: spi:MGAS10750_Spy1680 6.0e-15 replicative DNA helicase K01529; COG: COG1484 DNA replication protein; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.788
EDR48162.1
Hypothetical protein; KEGG: spi:MGAS10750_Spy1680 2.0e-14 replicative DNA helicase K01529; COG: COG1484 DNA replication protein; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.788
EDR48138.1
Hypothetical protein; KEGG: mge:MG_010 3.1e-05 DNA primase K02316.
  
 
 0.779
EDR45454.1
Hypothetical protein; KEGG: pfo:Pfl_0538 5.3e-05 DnaB helicase K02314; COG: NOG14428 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.779
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.774
EDR45685.1
Hypothetical protein.
   
 
 0.773
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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