STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR48257.1SPFH/Band 7/PHB domain protein; KEGG: reh:H16_A2036 2.1e-51 membrane protease subunits, stomatin/prohibitin homologs K01423; COG: COG0330 Membrane protease subunits, stomatin/prohibitin homologs; Psort location: Cytoplasmic, score: 8.87. (314 aa)    
Predicted Functional Partners:
hflB
ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.982
hflB-2
ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.982
hflB-3
ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.982
EDR48256.1
COG: COG1585 Membrane protein implicated in regulation of membrane protease activity; Psort location: CytoplasmicMembrane, score: 9.75.
 
  
 0.969
EDR46950.1
Hypothetical protein; KEGG: mmu:246104 0.0091 Rhbdl3; rhomboid, veinlet-like 3 (Drosophila); COG: COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); Psort location: CytoplasmicMembrane, score: 9.99.
   
 0.935
EDR46193.1
Peptidase, S54 family; KEGG: eci:UTI89_C0653 3.5e-23 hypothetical protein; COG: COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); Psort location: CytoplasmicMembrane, score: 9.99.
   
 0.935
EDR47968.1
Phosphoribulokinase/uridine kinase family protein; KEGG: cpe:CPE1347 1.3e-122 probable uridine kinase K00876; COG: COG0572 Uridine kinase; Psort location: Cytoplasmic, score: 8.87.
    
  0.865
EDR48544.1
KEGG: ctc:CTC01806 6.6e-199 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: COG1410 Methionine synthase I, cobalamin-binding domain; Psort location: Cytoplasmic, score: 8.87.
   
  0.844
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
       0.606
EDR48255.1
RNA methyltransferase, TrmH family, group 3; KEGG: gka:GK2709 7.7e-38 rRNA methylase K03437; COG: COG0566 rRNA methylases; Psort location: Cytoplasmic, score: 8.87; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
   0.585
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.