| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDR47142.1 | EDR47144.1 | DORFOR_01633 | DORFOR_01635 | Biotin-requiring enzyme; KEGG: sph:MGAS10270_Spy1010 2.1e-19 biotin carboxyl carrier protein of oxaloacetate decarboxylase K01570; COG: COG0511 Biotin carboxyl carrier protein. | Carboxyl transferase domain protein; KEGG: tte:TTE2385 6.0e-102 accA2; Acetyl-CoA carboxylase alpha subunit K01966; COG: COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.898 |
| EDR47142.1 | accC | DORFOR_01633 | DORFOR_01769 | Biotin-requiring enzyme; KEGG: sph:MGAS10270_Spy1010 2.1e-19 biotin carboxyl carrier protein of oxaloacetate decarboxylase K01570; COG: COG0511 Biotin carboxyl carrier protein. | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.935 |
| EDR47142.1 | accC-2 | DORFOR_01633 | DORFOR_01784 | Biotin-requiring enzyme; KEGG: sph:MGAS10270_Spy1010 2.1e-19 biotin carboxyl carrier protein of oxaloacetate decarboxylase K01570; COG: COG0511 Biotin carboxyl carrier protein. | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.935 |
| EDR47142.1 | birA | DORFOR_01633 | DORFOR_00384 | Biotin-requiring enzyme; KEGG: sph:MGAS10270_Spy1010 2.1e-19 biotin carboxyl carrier protein of oxaloacetate decarboxylase K01570; COG: COG0511 Biotin carboxyl carrier protein. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.921 |
| EDR47142.1 | pyc | DORFOR_01633 | DORFOR_03136 | Biotin-requiring enzyme; KEGG: sph:MGAS10270_Spy1010 2.1e-19 biotin carboxyl carrier protein of oxaloacetate decarboxylase K01570; COG: COG0511 Biotin carboxyl carrier protein. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.413 |
| EDR47144.1 | EDR47142.1 | DORFOR_01635 | DORFOR_01633 | Carboxyl transferase domain protein; KEGG: tte:TTE2385 6.0e-102 accA2; Acetyl-CoA carboxylase alpha subunit K01966; COG: COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | Biotin-requiring enzyme; KEGG: sph:MGAS10270_Spy1010 2.1e-19 biotin carboxyl carrier protein of oxaloacetate decarboxylase K01570; COG: COG0511 Biotin carboxyl carrier protein. | 0.898 |
| EDR47144.1 | accC | DORFOR_01635 | DORFOR_01769 | Carboxyl transferase domain protein; KEGG: tte:TTE2385 6.0e-102 accA2; Acetyl-CoA carboxylase alpha subunit K01966; COG: COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.998 |
| EDR47144.1 | accC-2 | DORFOR_01635 | DORFOR_01784 | Carboxyl transferase domain protein; KEGG: tte:TTE2385 6.0e-102 accA2; Acetyl-CoA carboxylase alpha subunit K01966; COG: COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.998 |
| EDR47144.1 | birA | DORFOR_01635 | DORFOR_00384 | Carboxyl transferase domain protein; KEGG: tte:TTE2385 6.0e-102 accA2; Acetyl-CoA carboxylase alpha subunit K01966; COG: COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.977 |
| EDR47144.1 | pyc | DORFOR_01635 | DORFOR_03136 | Carboxyl transferase domain protein; KEGG: tte:TTE2385 6.0e-102 accA2; Acetyl-CoA carboxylase alpha subunit K01966; COG: COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.963 |
| accC | EDR47142.1 | DORFOR_01769 | DORFOR_01633 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Biotin-requiring enzyme; KEGG: sph:MGAS10270_Spy1010 2.1e-19 biotin carboxyl carrier protein of oxaloacetate decarboxylase K01570; COG: COG0511 Biotin carboxyl carrier protein. | 0.935 |
| accC | EDR47144.1 | DORFOR_01769 | DORFOR_01635 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Carboxyl transferase domain protein; KEGG: tte:TTE2385 6.0e-102 accA2; Acetyl-CoA carboxylase alpha subunit K01966; COG: COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.998 |
| accC | birA | DORFOR_01769 | DORFOR_00384 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.977 |
| accC | pyc | DORFOR_01769 | DORFOR_03136 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.922 |
| accC-2 | EDR47142.1 | DORFOR_01784 | DORFOR_01633 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Biotin-requiring enzyme; KEGG: sph:MGAS10270_Spy1010 2.1e-19 biotin carboxyl carrier protein of oxaloacetate decarboxylase K01570; COG: COG0511 Biotin carboxyl carrier protein. | 0.935 |
| accC-2 | EDR47144.1 | DORFOR_01784 | DORFOR_01635 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Carboxyl transferase domain protein; KEGG: tte:TTE2385 6.0e-102 accA2; Acetyl-CoA carboxylase alpha subunit K01966; COG: COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.998 |
| accC-2 | birA | DORFOR_01784 | DORFOR_00384 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.977 |
| accC-2 | pyc | DORFOR_01784 | DORFOR_03136 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.922 |
| bioB | birA | DORFOR_03064 | DORFOR_00384 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.923 |
| bioB | hydE | DORFOR_03064 | DORFOR_00156 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Iron-only hydrogenase maturation rSAM protein HydE; KEGG: bth:BT1835 1.2e-103 biotin synthetase K01012; COG: COG0502 Biotin synthase and related enzymes; Psort location: Cytoplasmic, score: 8.87. | 0.859 |
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