Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR48266.1CAAX amino terminal protease family protein; KEGG: reh:H16_A3131 0.0031 pntB3; NAD(P) transhydrogenase subunit beta K00323; COG: COG1266 Predicted metal-dependent membrane protease; Psort location: CytoplasmicMembrane, score: 9.99. (278 aa)    
Predicted Functional Partners:
EDR48265.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.592
EDR48270.1
Lantibiotic protection ABC transporter permease subunit, MutG family; COG: NOG31276 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.478
EDR48267.1
Hypothetical protein.
       0.477
EDR48269.1
Lantibiotic protection ABC transporter permease subunit, MutE/EpiE family; COG: NOG17940 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.476
EDR48272.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00629 7.5e-72 spaK; subtilin biosynthesis sensor protein SpaK; COG: COG0642 Signal transduction histidine kinase.
 
     0.466
EDR48268.1
Lantibiotic protection ABC transporter, ATP-binding subunit; KEGG: fal:FRAAL3681 2.2e-40 putative ABC transporter ATP-binding protein; COG: COG1131 ABC-type multidrug transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
 
    0.451
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (12%) [HD]