Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR48287.1Lipase/acylhydrolase, GDSL family; KEGG: fra:Francci3_1861 4.7e-09 2-dehydropantoate 2-reductase K00077; COG: COG1893 Ketopantoate reductase. (315 aa)    
Predicted Functional Partners:
EDR45599.1
Ketopantoate reductase PanE/ApbA; KEGG: fra:Francci3_1861 3.0e-09 2-dehydropantoate 2-reductase K00077; COG: COG1893 Ketopantoate reductase; Psort location: Cytoplasmic, score: 8.87.
  
  
 
0.900
EDR48288.1
Hypothetical protein; KEGG: sru:SRU_1592 4.5e-17 menaquinone biosynthesis methyltransferase UbiE K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87.
 
     0.813
EDR48289.1
Hypothetical protein; COG: NOG21754 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.803
EDR48290.1
Hypothetical protein; KEGG: mbo:Mb0533 1.5e-05 possible methyltransferase/methylase (fragment) K00599; COG: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis.
 
     0.716
EDR48286.1
Hypothetical protein; COG: COG0428 Predicted divalent heavy-metal cations transporter.
       0.527
sdhB
KEGG: sha:SH1812 1.0e-35 sdhB; succinate dehydrogenase iron-sulfur protein subunit K00240; COG: COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
  
     0.455
sdhA
KEGG: gka:GK2672 5.6e-83 sdhA; succinate dehydrogenase (flavoprotein subunit) K00239; COG: COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Psort location: Cytoplasmic, score: 9.36.
  
     0.440
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.