| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDR45822.1 | EDR46541.1 | DORFOR_02423 | DORFOR_01763 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 2.1e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | 0.623 |
| EDR45822.1 | EDR48199.1 | DORFOR_02423 | DORFOR_00540 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 2.1e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | Response regulator receiver domain protein; KEGG: eci:UTI89_C0420 1.3e-28 phoB; positive response regulator for pho regulon K07657; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.65. | 0.746 |
| EDR45822.1 | EDR48218.1 | DORFOR_02423 | DORFOR_00342 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 2.1e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | Hypothetical protein; KEGG: abo:ABO_0442 8.9e-07 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 8.87. | 0.882 |
| EDR45822.1 | EDR48301.1 | DORFOR_02423 | DORFOR_00426 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 2.1e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | Hypothetical protein; KEGG: tcx:Tcr_2180 1.1e-64 PAS/PAC sensor hybrid histidine kinase K07679; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.537 |
| EDR45822.1 | EDR48417.1 | DORFOR_02423 | DORFOR_00159 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 2.1e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | Hypothetical protein. | 0.481 |
| EDR46391.1 | EDR46541.1 | DORFOR_03003 | DORFOR_01763 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2042 8.2e-50 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | 0.906 |
| EDR46391.1 | EDR48199.1 | DORFOR_03003 | DORFOR_00540 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2042 8.2e-50 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Response regulator receiver domain protein; KEGG: eci:UTI89_C0420 1.3e-28 phoB; positive response regulator for pho regulon K07657; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.65. | 0.854 |
| EDR46391.1 | EDR48218.1 | DORFOR_03003 | DORFOR_00342 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2042 8.2e-50 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Hypothetical protein; KEGG: abo:ABO_0442 8.9e-07 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 8.87. | 0.971 |
| EDR46391.1 | EDR48301.1 | DORFOR_03003 | DORFOR_00426 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2042 8.2e-50 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Hypothetical protein; KEGG: tcx:Tcr_2180 1.1e-64 PAS/PAC sensor hybrid histidine kinase K07679; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.457 |
| EDR46391.1 | EDR48417.1 | DORFOR_03003 | DORFOR_00159 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2042 8.2e-50 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Hypothetical protein. | 0.592 |
| EDR46541.1 | EDR45822.1 | DORFOR_01763 | DORFOR_02423 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 2.1e-42 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | 0.623 |
| EDR46541.1 | EDR46391.1 | DORFOR_01763 | DORFOR_03003 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2042 8.2e-50 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.906 |
| EDR46541.1 | EDR47325.1 | DORFOR_01763 | DORFOR_01291 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: sag:SAG1960 5.3e-62 sensor histidine kinase K02484; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.900 |
| EDR46541.1 | EDR48198.1 | DORFOR_01763 | DORFOR_00539 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2042 3.3e-53 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.922 |
| EDR46541.1 | EDR48199.1 | DORFOR_01763 | DORFOR_00540 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | Response regulator receiver domain protein; KEGG: eci:UTI89_C0420 1.3e-28 phoB; positive response regulator for pho regulon K07657; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.65. | 0.850 |
| EDR46541.1 | EDR48218.1 | DORFOR_01763 | DORFOR_00342 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: abo:ABO_0442 8.9e-07 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 8.87. | 0.999 |
| EDR46541.1 | EDR48301.1 | DORFOR_01763 | DORFOR_00426 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: tcx:Tcr_2180 1.1e-64 PAS/PAC sensor hybrid histidine kinase K07679; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.999 |
| EDR46541.1 | EDR48417.1 | DORFOR_01763 | DORFOR_00159 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein. | 0.998 |
| EDR46541.1 | cobA | DORFOR_01763 | DORFOR_02965 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | uroporphyrinogen-III C-methyltransferase; KEGG: cno:NT01CX_0261 1.5e-89 uroporphyrinogen III synthase/methyltransferase K00589; COG: COG1587 Uroporphyrinogen-III synthase; Psort location: Cytoplasmic, score: 8.87. | 0.405 |
| EDR46541.1 | hemC | DORFOR_01763 | DORFOR_02964 | Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.405 |