STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR47904.1NADH pyrophosphatase zinc ribbon domain protein; KEGG: lpl:lp_3123 8.2e-50 pyrophosphatase (putative) K03659; COG: COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Psort location: Cytoplasmic, score: 8.87. (326 aa)    
Predicted Functional Partners:
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
 
 0.923
cobB-2
Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
   
  0.910
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
    
 0.910
nadC
Nicotinate-nucleotide diphosphorylase (carboxylating); KEGG: fnu:FN0010 1.8e-84 nicotinate-nucleotide pyrophosphorylase K00767; COG: COG0157 Nicotinate-nucleotide pyrophosphorylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the NadC/ModD family.
     
  0.900
EDR47905.1
KEGG: cno:NT01CX_0861 5.8e-152 gyrA; DNA gyrase, A subunit K01863; COG: COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; Psort location: Cytoplasmic, score: 8.87.
       0.779
EDR47906.1
DNA gyrase, B subunit, C-terminal domain protein; KEGG: bsu:BG10070 4.1e-174 gyrB, novA; DNA gyrase subunit B K02470; COG: COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; Psort location: Cytoplasmic, score: 8.87.
       0.733
spoIIP
Stage II sporulation protein P (SpoIIP); COG: NOG13213 non supervised orthologous group.
       0.493
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.