STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gprGPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. (326 aa)    
Predicted Functional Partners:
spoIIP
Stage II sporulation protein P (SpoIIP); COG: NOG13213 non supervised orthologous group.
 
    0.923
spoVAD
Stage V sporulation protein AD; KEGG: mma:MM0870 0.0025 acetyl-CoA acyltransferase K00632; COG: NOG06312 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.921
EDR47425.1
Putative stage V sporulation protein AC; COG: NOG09745 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.26.
  
  
 0.858
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.828
EDR47109.1
Small, acid-soluble spore protein, alpha/beta type; COG: NOG16862 non supervised orthologous group.
  
  
 0.828
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.821
spo0A
Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.812
spoVT
Stage V sporulation protein T; COG: COG2002 Regulators of stationary/sporulation gene expression; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.788
EDR47505.1
Sporulation initiation factor Spo0A domain protein; COG: COG0784 FOG: CheY-like receiver; Psort location: Cytoplasmic, score: 8.87.
  
   
 0.784
EDR47222.1
Hypothetical protein; COG: NOG05963 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.26.
  
    0.784
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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