STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gprGPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. (326 aa)    
Predicted Functional Partners:
spoIIP
Stage II sporulation protein P (SpoIIP); COG: NOG13213 non supervised orthologous group.
 
    0.921
spoVAD
Stage V sporulation protein AD; KEGG: mma:MM0870 0.0025 acetyl-CoA acyltransferase K00632; COG: NOG06312 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.910
EDR47425.1
Putative stage V sporulation protein AC; COG: NOG09745 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.26.
  
  
 0.854
EDR47109.1
Small, acid-soluble spore protein, alpha/beta type; COG: NOG16862 non supervised orthologous group.
  
  
 0.809
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.806
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.797
EDR47222.1
Hypothetical protein; COG: NOG05963 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.26.
  
    0.787
EDR47412.1
Putative stage V sporulation protein AE; COG: NOG13202 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.26.
  
    0.777
yabP
Sporulation protein YabP; COG: NOG13819 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
   
 0.777
spoIVB
SpoIVB peptidase; KEGG: btl:BALH_3781 2.2e-49 spoIVB; stage IV sporulation protein B; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1; Psort location: Cytoplasmic, score: 8.87.
  
     0.774
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.