STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR47913.1Metallo-beta-lactamase domain protein; KEGG: nmu:Nmul_A1621 0.0028 hydroxyacylglutathione hydrolase K01069; COG: COG2247 Putative cell wall-binding domain. (306 aa)    
Predicted Functional Partners:
EDR47914.1
Hypothetical protein; COG: COG4887 Uncharacterized metal-binding protein conserved in archaea; Psort location: Cytoplasmic, score: 8.87.
       0.566
ilvN
KEGG: chy:CHY_1594 4.3e-37 ilvN2; acetolactate synthase, small subunit K01653; COG: COG0440 Acetolactate synthase, small (regulatory) subunit; Psort location: Cytoplasmic, score: 8.87.
       0.497
EDR48459.1
comF family protein; KEGG: reh:H16_A0339 6.5e-18 predicted amidophosphoribosyltransferase; COG: COG1040 Predicted amidophosphoribosyltransferases; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.475
dprA
DNA protecting protein DprA; COG: COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.472
EDR45880.1
comEA protein; COG: COG1555 DNA uptake protein and related DNA-binding proteins; Psort location: CytoplasmicMembrane, score: 9.49.
 
  
 0.453
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.448
EDR47165.1
Bacterial peptidase A24, N-terminal domain protein; KEGG: ppd:Ppro_0982 1.4e-36 prepilin peptidase; COG: COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.438
EDR47915.1
KEGG: shn:Shewana3_3300 1.8e-13 chromate transporter, chromate ion transporter (CHR) family K00229; COG: COG2059 Chromate transport protein ChrA; Psort location: CytoplasmicMembrane, score: 9.99.
       0.433
EDR47916.1
KEGG: shn:Shewana3_3300 3.0e-13 chromate transporter, chromate ion transporter (CHR) family K00229; COG: COG2059 Chromate transport protein ChrA; Psort location: CytoplasmicMembrane, score: 9.99.
       0.433
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.421
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.