Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyrIAspartate carbamoyltransferase regulatory chain, allosteric domain protein; KEGG: cac:CAC2653 6.6e-32 pyrI; aspartate carbamoyltransferase regulatory subunit K00610; COG: COG1781 Aspartate carbamoyltransferase, regulatory subunit; Psort location: Cytoplasmic, score: 8.87. (151 aa)    
Predicted Functional Partners:
pyrB
KEGG: cac:CAC2654 8.0e-107 aspartate carbamoyltransferase catalytic subunit K00609; COG: COG0540 Aspartate carbamoyltransferase, catalytic chain; Psort location: Cytoplasmic, score: 9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
 
 0.999
carB
KEGG: cpe:CPE2572 0. carB; carbamoyl-phosphate synthetase catalytic subunit K01955; COG: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Psort location: Cytoplasmic, score: 8.87.
  
 
 0.978
carA
KEGG: ldb:Ldb1070 1.2e-110 carA2a; carbamoyl-phosphate synthase small chain K01954; COG: COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family.
  
 
 0.956
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
    
 0.919
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.908
asnA
Aspartate--ammonia ligase; KEGG: lsl:LSL_1033 3.7e-134 asnA; aspartate--ammonia ligase K01914; COG: COG2502 Asparagine synthetase A; Psort location: Cytoplasmic, score: 10.00.
     
  0.900
argG
KEGG: lma:LmjF23.0260 3.0e-132 argininosuccinate synthase, putative K01940; COG: COG0137 Argininosuccinate synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
  0.900
EDR47566.1
KEGG: ctc:CTC00824 3.1e-169 aspartate ammonia-lyase, aspartase K01744; COG: COG1027 Aspartate ammonia-lyase; Psort location: Cytoplasmic, score: 9.98.
     
  0.900
EDR47014.1
FAD binding domain protein; KEGG: cpf:CPF_0383 8.8e-101 nadB; L-aspartate oxidase K00278; COG: COG0029 Aspartate oxidase; Psort location: Cytoplasmic, score: 9.36.
     
  0.900
EDR45850.1
Aminotransferase, class I/II; KEGG: cac:CAC2832 5.0e-114 PLP-dependent aminotransferase K00811; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score: 8.87.
     
  0.900
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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