Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rnhARibonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (150 aa)    
Predicted Functional Partners:
EDR47936.1
Molybdenum cofactor synthesis domain protein; KEGG: hpa:HPAG1_0784 3.0e-20 molybdopterin biosynthesis protein; COG: COG0521 Molybdopterin biosynthesis enzymes.
       0.780
EDR47935.1
Hypothetical protein; KEGG: fnu:FN1387 1.7e-33 metal dependent hydrolase; COG: COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; Psort location: Cytoplasmic, score: 8.87.
       0.776
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.774
EDR48245.1
KEGG: shn:Shewana3_3590 1.1e-18 single-strand binding protein K00655; COG: COG0629 Single-stranded DNA-binding protein; Psort location: Cytoplasmic, score: 8.87.
   
 0.546
EDR48048.1
COG: COG0629 Single-stranded DNA-binding protein; Psort location: Cytoplasmic, score: 8.87.
   
 0.546
EDR46692.1
Single-strand binding family protein; KEGG: xom:XOO_2030 0.00013 XOO2030; pseudouridylate synthase K06178; COG: KOG3544 Collagens (type IV and type XIII), and related proteins.
   
 0.546
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.543
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.532
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
       0.521
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
   
 
 0.492
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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