STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIVAStage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (496 aa)    
Predicted Functional Partners:
EDR48522.1
Putative stage III sporulation protein AD; COG: NOG13205 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 7.63.
  
  
 0.902
EDR46158.1
SpoIID/LytB domain protein; COG: COG2385 Sporulation protein and related proteins.
  
  
 0.872
spoIIID
Sporulation transcriptional regulator SpoIIID; COG: NOG13855 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.856
EDR48519.1
Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.853
EDR48525.1
Putative stage III sporulation protein AG; COG: NOG11553 non supervised orthologous group.
  
  
 0.830
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.823
EDR47431.1
KEGG: ava:Ava_0744 0.00013 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.
  
   
 0.820
EDR47787.1
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.816
spoIIR
Stage II sporulation protein R; COG: NOG13215 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
   
 0.816
EDR47105.1
Putative sporulation integral membrane protein YlbJ; COG: COG3314 Uncharacterized protein conserved in bacteria; Psort location: CytoplasmicMembrane, score: 9.99.
  
   
 0.812
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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