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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prsRibose-phosphate diphosphokinase; KEGG: cac:CAC0819 9.8e-102 phosphoribosylpyrophosphate synthetase K00948; COG: COG0462 Phosphoribosylpyrophosphate synthetase; Psort location: CytoplasmicMembrane, score: 7.80; Belongs to the ribose-phosphate pyrophosphokinase family. (405 aa)    
Predicted Functional Partners:
lpdA
Dihydrolipoyl dehydrogenase; KEGG: ctc:CTC02047 2.4e-98 dihydrolipoamide dehydrogenase K00382; COG: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; Psort location: Cytoplasmic, score: 9.98.
   
 0.929
EDR45671.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
   
 0.929
EDR46920.1
KEGG: ctc:CTC02045 3.7e-77 lipoate-protein ligase A K03800; COG: COG0095 Lipoate-protein ligase A; Psort location: Cytoplasmic, score: 9.98.
   
 
  0.909
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
 0.867
EDR48306.1
Hypothetical protein; KEGG: cpr:CPR_1841 1.2e-128 phosphomannomutase K01840; COG: COG1109 Phosphomannomutase; Psort location: Cytoplasmic, score: 8.87.
  
 0.825
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
  
 
 0.813
rpiB
KEGG: sth:STH2337 5.9e-56 ribose 5-phosphate isomerase K01808; COG: COG0698 Ribose 5-phosphate isomerase RpiB; Psort location: Cytoplasmic, score: 8.87.
    
 0.809
EDR47284.1
Kinase, PfkB family; KEGG: btl:BALH_0607 2.3e-22 rbsK; ribokinase K00852; COG: COG0524 Sugar kinases, ribokinase family; Psort location: Cytoplasmic, score: 8.87.
    
 0.797
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.797
EDR46931.1
Hydrolase, NUDIX family; KEGG: tte:TTE1310 1.3e-33 mutT2; NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.795
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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