| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDR45447.1 | rpmC | DORFOR_03231 | DORFOR_01351 | DNA-binding helix-turn-helix protein; COG: COG1396 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87. | COG: COG0255 Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. | 0.892 |
| EDR45447.1 | secA | DORFOR_03231 | DORFOR_00699 | DNA-binding helix-turn-helix protein; COG: COG1396 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.873 |
| EDR46010.1 | ffh | DORFOR_02617 | DORFOR_01692 | Putative ATP synthase F0, A subunit; COG: COG0706 Preprotein translocase subunit YidC; Psort location: CytoplasmicMembrane, score: 9.99. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.912 |
| EDR46010.1 | ftsY | DORFOR_02617 | DORFOR_01476 | Putative ATP synthase F0, A subunit; COG: COG0706 Preprotein translocase subunit YidC; Psort location: CytoplasmicMembrane, score: 9.99. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.894 |
| EDR46010.1 | secA | DORFOR_02617 | DORFOR_00699 | Putative ATP synthase F0, A subunit; COG: COG0706 Preprotein translocase subunit YidC; Psort location: CytoplasmicMembrane, score: 9.99. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.933 |
| EDR46010.1 | secD | DORFOR_02617 | DORFOR_00851 | Putative ATP synthase F0, A subunit; COG: COG0706 Preprotein translocase subunit YidC; Psort location: CytoplasmicMembrane, score: 9.99. | Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.998 |
| EDR46010.1 | secE | DORFOR_02617 | DORFOR_01206 | Putative ATP synthase F0, A subunit; COG: COG0706 Preprotein translocase subunit YidC; Psort location: CytoplasmicMembrane, score: 9.99. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.982 |
| EDR46010.1 | secG | DORFOR_02617 | DORFOR_02536 | Putative ATP synthase F0, A subunit; COG: COG0706 Preprotein translocase subunit YidC; Psort location: CytoplasmicMembrane, score: 9.99. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.987 |
| EDR46010.1 | secY | DORFOR_02617 | DORFOR_01339 | Putative ATP synthase F0, A subunit; COG: COG0706 Preprotein translocase subunit YidC; Psort location: CytoplasmicMembrane, score: 9.99. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.993 |
| EDR46010.1 | yajC | DORFOR_02617 | DORFOR_00609 | Putative ATP synthase F0, A subunit; COG: COG0706 Preprotein translocase subunit YidC; Psort location: CytoplasmicMembrane, score: 9.99. | COG: COG1862 Preprotein translocase subunit YajC. | 0.899 |
| ffh | EDR46010.1 | DORFOR_01692 | DORFOR_02617 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Putative ATP synthase F0, A subunit; COG: COG0706 Preprotein translocase subunit YidC; Psort location: CytoplasmicMembrane, score: 9.99. | 0.912 |
| ffh | ftsY | DORFOR_01692 | DORFOR_01476 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.995 |
| ffh | rpmC | DORFOR_01692 | DORFOR_01351 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | COG: COG0255 Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. | 0.942 |
| ffh | secA | DORFOR_01692 | DORFOR_00699 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.921 |
| ffh | secD | DORFOR_01692 | DORFOR_00851 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.935 |
| ffh | secE | DORFOR_01692 | DORFOR_01206 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.982 |
| ffh | secG | DORFOR_01692 | DORFOR_02536 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.974 |
| ffh | secY | DORFOR_01692 | DORFOR_01339 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.989 |
| ffh | yajC | DORFOR_01692 | DORFOR_00609 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | COG: COG1862 Preprotein translocase subunit YajC. | 0.889 |
| ftsY | EDR46010.1 | DORFOR_01476 | DORFOR_02617 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Putative ATP synthase F0, A subunit; COG: COG0706 Preprotein translocase subunit YidC; Psort location: CytoplasmicMembrane, score: 9.99. | 0.894 |