Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR48060.1AMP-binding enzyme; KEGG: bca:BCE_0965 4.7e-70 AMP-binding protein K01897; COG: COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; Psort location: Cytoplasmic, score: 9.98. (547 aa)    
Predicted Functional Partners:
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.895
EDR47300.1
PAP2 family protein; KEGG: aci:ACIAD0554 7.9e-13 putative phosphatidylglycerophosphatase B (PgpB) K01094; COG: COG0671 Membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 9.26.
    
  0.781
EDR48467.1
Hypothetical protein; KEGG: lla:L90005 2.3e-06 dltC; D-alanyl carrier protein K03367; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.771
EDR47099.1
KEGG: nwi:Nwi_0477 5.4e-30 short-chain dehydrogenase/reductase SDR; COG: COG0300 Short-chain dehydrogenases of various substrate specificities; Psort location: Cytoplasmic, score: 8.87; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.736
EDR45496.1
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 
 0.733
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
   0.730
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
    
   0.726
rplX
Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
    
   0.724
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
   0.722
rplQ
COG: COG0203 Ribosomal protein L17; Psort location: Cytoplasmic, score: 8.87.
    
   0.720
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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