Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nadENAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (639 aa)    
Predicted Functional Partners:
cobB-2
Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
    
 0.940
EDR47904.1
NADH pyrophosphatase zinc ribbon domain protein; KEGG: lpl:lp_3123 8.2e-50 pyrophosphatase (putative) K03659; COG: COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.923
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.806
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.753
EDR48324.1
Cytidyltransferase-related domain protein; KEGG: tko:TK0067 1.0e-10 nicotinamide mononucleotide adenylyltransferase K00952; COG: COG1056 Nicotinamide mononucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 8.87.
    
 0.749
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  
  
 0.737
cobA
uroporphyrinogen-III C-methyltransferase; KEGG: cno:NT01CX_0261 1.5e-89 uroporphyrinogen III synthase/methyltransferase K00589; COG: COG1587 Uroporphyrinogen-III synthase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.737
EDR48283.1
Competence/damage-inducible domain protein CinA; COG: COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Psort location: Cytoplasmic, score: 8.87; Belongs to the CinA family.
     
 0.735
EDR48294.1
Hypothetical protein; COG: COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Psort location: Cytoplasmic, score: 8.87; Belongs to the CinA family.
     
 0.735
EDR48035.1
DJ-1 family protein; KEGG: lic:LIC11685 3.1e-27 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis K03152; COG: COG0693 Putative intracellular protease/amidase; Psort location: Cytoplasmic, score: 8.87.
 
   0.730
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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