Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
recJKEGG: cac:CAC2232 2.2e-143 recJ; SsDNA exonuclease, RecJ K07462; COG: COG0608 Single-stranded DNA-specific exonuclease; Psort location: Cytoplasmic, score: 8.87. (580 aa)    
Predicted Functional Partners:
secD
Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
   
 0.769
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
    0.710
EDR47763.1
Putative histidine--tRNA ligase; KEGG: lxx:Lxx17220 8.9e-76 hisS; histidyl-tRNA synthetase K01892; COG: COG0124 Histidyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
   0.700
EDR47765.1
Metallo-beta-lactamase domain protein; KEGG: ctc:CTC02196 1.0e-35 hydroxyacylglutathione hydrolase K01069; COG: COG0491 Zn-dependent hydrolases, including glyoxylases; Psort location: Cytoplasmic, score: 8.87.
  
    0.667
hemZ
KEGG: cpe:CPE1935 9.2e-90 hemZ; probable coproporphyrinogen III oxidase K02495; COG: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 9.98.
  
    0.665
dprA
DNA protecting protein DprA; COG: COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.663
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
     0.657
EDR47766.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
    0.638
mutL
DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
  
 0.587
aspS-2
aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.586
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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