STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR47791.1KEGG: gka:GK1126 3.2e-10 spoIIGA; protease (sporulation sigma-E factor processing peptidase); COG: NOG09744 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99. (258 aa)    
Predicted Functional Partners:
EDR46296.1
Putative stage II sporulation protein E; KEGG: tte:TTE2396 6.0e-54 rsbU; serine phosphatase RsbU, regulator of sigma subunit K06382; COG: COG2208 Serine phosphatase RsbU, regulator of sigma subunit; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.893
EDR48526.1
Hypothetical protein; COG: NOG17862 non supervised orthologous group.
  
  
 0.803
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.793
sigE
RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.768
spoIIP
Stage II sporulation protein P (SpoIIP); COG: NOG13213 non supervised orthologous group.
  
   
 0.759
EDR46591.1
LysM domain protein; COG: COG1388 FOG: LysM repeat; Psort location: Cytoplasmic, score: 8.87.
  
    0.755
EDR47787.1
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.745
EDR47105.1
Putative sporulation integral membrane protein YlbJ; COG: COG3314 Uncharacterized protein conserved in bacteria; Psort location: CytoplasmicMembrane, score: 9.99.
  
   
 0.737
EDR47020.1
Putative sporulation protein YqfD; COG: NOG07866 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
   
 0.736
spoIIR
Stage II sporulation protein R; COG: NOG13215 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.732
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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