STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR47826.1Hypothetical protein; Psort location: Extracellular, score: 7.50. (45 aa)    
Predicted Functional Partners:
sigK
RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.572
dprA
DNA protecting protein DprA; COG: COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; Psort location: Cytoplasmic, score: 8.87.
       0.542
EDR47824.1
Mg chelatase-like protein; KEGG: chu:CHU_0354 3.7e-118 ch1I; magnesium chelatase, subunit ChlI K07391; COG: COG0606 Predicted ATPase with chaperone activity; Psort location: Cytoplasmic, score: 8.87.
       0.542
EDR47827.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: tte:TTE1202 5.1e-41 baeS6; Sensory transduction histidine kinases K07717; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.99.
       0.449
EDR47828.1
YcbB domain protein; KEGG: eci:UTI89_C4457 5.9e-11 glnG; nitrogen regulation protein NR(I) K07712; COG: COG0784 FOG: CheY-like receiver; Psort location: Cytoplasmic, score: 8.87.
       0.449
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.411
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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