Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR47827.1ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: tte:TTE1202 5.1e-41 baeS6; Sensory transduction histidine kinases K07717; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.99. (426 aa)    
Predicted Functional Partners:
EDR47828.1
YcbB domain protein; KEGG: eci:UTI89_C4457 5.9e-11 glnG; nitrogen regulation protein NR(I) K07712; COG: COG0784 FOG: CheY-like receiver; Psort location: Cytoplasmic, score: 8.87.
 
 
 
 0.958
pfoR
Perfringolysin O regulator protein; KEGG: lin:lin0377 9.0e-10 similar to PTS system, fructose-specific enzyme IIBC component K02769:K02770; COG: COG1299 Phosphotransferase system, fructose-specific IIC component; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.817
EDR46541.1
Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 1.4e-45 sensory transduction protein kinase; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.711
EDR48417.1
Hypothetical protein.
  
 
 0.658
EDR46822.1
Response regulator receiver domain protein; KEGG: chu:CHU_2895 4.1e-66 sensory box histidine kinase/response regulator; COG: COG2203 FOG: GAF domain; Psort location: Cytoplasmic, score: 9.36.
 
 
 0.649
EDR48301.1
Hypothetical protein; KEGG: tcx:Tcr_2180 1.1e-64 PAS/PAC sensor hybrid histidine kinase K07679; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
 0.647
sigK
RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.594
EDR48218.1
Hypothetical protein; KEGG: abo:ABO_0442 8.9e-07 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.583
EDR48419.1
HD domain protein; KEGG: ava:Ava_1777 1.5e-43 metal dependent phosphohydrolase, HD region with response regulator receiver modulation K07814; COG: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; Psort location: Cytoplasmic, score: 8.87.
 
 
 
 0.538
EDR47169.1
Hypothetical protein.
  
     0.535
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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