STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR47844.1Aminotransferase, class V; KEGG: tte:TTE1663 1.2e-105 nifS; Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes K04487; COG: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Psort location: Cytoplasmic, score: 8.87. (385 aa)    
Predicted Functional Partners:
nifU
Fe-S iron-sulfur cluster assembly protein, NifU family; KEGG: rxy:Rxyl_1354 1.2e-20 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566; COG: COG0822 NifU homolog involved in Fe-S cluster formation; Psort location: Cytoplasmic, score: 8.87.
 
 0.998
EDR47920.1
Hypothetical protein; COG: COG0822 NifU homolog involved in Fe-S cluster formation; Psort location: Cytoplasmic, score: 8.87.
  
 0.996
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 0.990
EDR48396.1
Hypothetical protein; COG: NOG13230 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87; Belongs to the sulfur carrier protein TusA family.
   
 0.980
EDR46346.1
COG: COG0425 Predicted redox protein, regulator of disulfide bond formation; Psort location: Cytoplasmic, score: 8.87; Belongs to the sulfur carrier protein TusA family.
   
 0.967
EDR46349.1
ThiF family protein; KEGG: hpa:HPAG1_0799 3.4e-60 thiamine biosynthesis protein; COG: COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; Psort location: Cytoplasmic, score: 8.87.
   
 0.947
yedF
Selenium metabolism protein YedF; COG: NOG13230 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87; Belongs to the sulfur carrier protein TusA family.
   
 0.914
nifS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
  
 
0.863
EDR48434.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: btl:BALH_0703 2.0e-140 ndh; NADH dehydrogenase K00356; COG: COG0607 Rhodanese-related sulfurtransferase; Psort location: Cytoplasmic, score: 9.98.
   
 0.823
selD
KEGG: cpf:CPF_2374 2.4e-82 selD; selenide, water dikinase K01008; COG: COG0709 Selenophosphate synthase; Psort location: Cytoplasmic, score: 8.87.
   
 0.721
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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