Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR47465.1Putative calcium-translocating P-type ATPase, PMCA-type; KEGG: cpe:CPE0333 1.1e-278 probable cation-transporting ATPase K01529; COG: COG0474 Cation transport ATPase; Psort location: CytoplasmicMembrane, score: 10.00. (847 aa)    
Predicted Functional Partners:
EDR47466.1
Hypothetical protein; KEGG: tbd:Tbd_2668 2.1e-10 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; COG: COG0628 Predicted permease; Psort location: CytoplasmicMembrane, score: 9.99.
  
    0.662
rpsH
Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
    
   0.610
rpsM
30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
    
   0.575
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
    
   0.550
EDR48234.1
Hypothetical protein; COG: NOG16635 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
  
 
 0.549
rplD
50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
    
   0.519
EDR47352.1
Aldehyde dehydrogenase (NAD) family protein; KEGG: cpe:CPE2531 0. adhE; alcohol dehydrogenase / acetaldehyde dehydrogenase K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
   
 0.480
EDR48257.1
SPFH/Band 7/PHB domain protein; KEGG: reh:H16_A2036 2.1e-51 membrane protease subunits, stomatin/prohibitin homologs K01423; COG: COG0330 Membrane protease subunits, stomatin/prohibitin homologs; Psort location: Cytoplasmic, score: 8.87.
   
  0.473
pyk
Pyruvate kinase; KEGG: tte:TTE1815 2.8e-136 pykF; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.452
EDR48568.1
Copper-exporting ATPase; KEGG: tde:TDE0008 2.6e-188 copper-translocating P-type ATPase K01533; COG: COG2217 Cation transport ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
 
0.449
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.