STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR47505.1Sporulation initiation factor Spo0A domain protein; COG: COG0784 FOG: CheY-like receiver; Psort location: Cytoplasmic, score: 8.87. (115 aa)    
Predicted Functional Partners:
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.830
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.825
EDR47787.1
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.824
sigK
RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.824
spoIIID
Sporulation transcriptional regulator SpoIIID; COG: NOG13855 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
   
 0.821
EDR47431.1
KEGG: ava:Ava_0744 0.00013 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.
  
  
 0.816
EDR48519.1
Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.808
sigE
RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.808
spoVT
Stage V sporulation protein T; COG: COG2002 Regulators of stationary/sporulation gene expression; Psort location: Cytoplasmic, score: 9.98.
  
   
 0.807
spo0A
Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 
0.806
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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