Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sbcDExonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (378 aa)    
Predicted Functional Partners:
EDR47568.1
KEGG: ctc:CTC00579 3.0e-107 sbcC; exonuclease sbcC K03546; COG: COG0419 ATPase involved in DNA repair; Psort location: Cytoplasmic, score: 9.98.
 
 0.998
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.980
EDR46261.1
Hypothetical protein; KEGG: cal:orf19.2417 2.5e-07 SMC5; structural maintenance of chromosomes protein K01553; COG: COG4717 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
  
 0.960
EDR45655.1
Topoisomerase DNA-binding C4 zinc finger domain protein; KEGG: pab:PAB1430 5.2e-06 topA; DNA topoisomerase I K03168; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.87.
   
 0.921
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.885
EDR47712.1
DEAD2 domain protein; KEGG: mja:MJ0942 6.8e-25 dinG; ATP-dependent DNA helicase DinG, putative K01529; COG: COG1199 Rad3-related DNA helicases; Psort location: Cytoplasmic, score: 8.87.
   
 0.841
EDR45506.1
Hypothetical protein; COG: NOG13188 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
   
 0.741
sulP
Sulfate permease; KEGG: lpn:lpg0697 1.9e-25 sul1; sulfate transporter K01672; COG: COG0659 Sulfate permease and related transporters (MFS superfamily).
   
   0.688
EDR46453.1
Hypothetical protein; KEGG: eci:UTI89_C1400 5.8e-15 ychM; putative sulfate transporter YchM K03321; COG: COG0659 Sulfate permease and related transporters (MFS superfamily).
   
   0.688
EDR47983.1
UvrD/REP helicase; KEGG: cac:CAC1003 6.9e-91 superfamily I DNA helicase (rep-like helicase) K01529; COG: COG0210 Superfamily I DNA and RNA helicases; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.585
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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