Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rpiBKEGG: sth:STH2337 5.9e-56 ribose 5-phosphate isomerase K01808; COG: COG0698 Ribose 5-phosphate isomerase RpiB; Psort location: Cytoplasmic, score: 8.87. (154 aa)    
Predicted Functional Partners:
rpe
KEGG: cpe:CPE1736 1.1e-59 ribulose-phosphate 3-epimerase K01783; COG: COG0036 Pentose-5-phosphate-3-epimerase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.939
EDR46322.1
Transketolase, pyridine binding domain protein; KEGG: chy:CHY_0166 2.3e-84 putative transketolase, C-terminal subunit K00615; COG: COG3958 Transketolase, C-terminal subunit; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.927
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
    
 0.922
EDR46321.1
Transketolase, thiamine diphosphate binding domain protein; KEGG: mmp:MMP1115 2.1e-76 transketolase, N terminal half K00615; COG: COG3959 Transketolase, N-terminal subunit.
 
  
 0.922
prs
Ribose-phosphate diphosphokinase; KEGG: cac:CAC0819 9.8e-102 phosphoribosylpyrophosphate synthetase K00948; COG: COG0462 Phosphoribosylpyrophosphate synthetase; Psort location: CytoplasmicMembrane, score: 7.80; Belongs to the ribose-phosphate pyrophosphokinase family.
  
 
 0.921
prs-2
KEGG: cpr:CPR_1519 1.9e-98 prs; ribose-phosphate pyrophosphokinase K00948; COG: COG0462 Phosphoribosylpyrophosphate synthetase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.921
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
     
 0.918
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
  
 0.916
glyA-2
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
  
 0.914
EDR48306.1
Hypothetical protein; KEGG: cpr:CPR_1841 1.2e-128 phosphomannomutase K01840; COG: COG1109 Phosphomannomutase; Psort location: Cytoplasmic, score: 8.87.
     
 0.906
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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