Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
crhHPr-like protein crh; KEGG: btl:BALH_4643 1.3e-10 ptsH; phosphocarrier protein HPr K00889; COG: COG1925 Phosphotransferase system, HPr-related proteins; Psort location: Cytoplasmic, score: 9.65. (87 aa)    
Predicted Functional Partners:
ptsP-2
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.978
ptsP
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.977
EDR45569.1
KEGG: cpr:CPR_0550 2.6e-163 fructose specific permease K00890; COG: COG1299 Phosphotransferase system, fructose-specific IIC component; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.973
EDR48464.1
Phosphocarrier, HPr family; KEGG: btl:BALH_3665 2.4e-11 ptsH; phosphocarrier protein HPr K00889; COG: COG1925 Phosphotransferase system, HPr-related proteins; Psort location: Cytoplasmic, score: 9.98.
  
  
  0.960
EDR45809.1
PTS system fructose IIA component; KEGG: ljo:LJ0742 3.8e-36 phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA, probable mannose specific K02793; COG: COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; Psort location: Cytoplasmic, score: 8.87.
   
 0.935
ptsH
Phosphocarrier protein HPr; KEGG: btl:BALH_3665 1.4e-15 ptsH; phosphocarrier protein HPr K00889; COG: COG1925 Phosphotransferase system, HPr-related proteins; Psort location: Cytoplasmic, score: 10.00.
  
  
 
0.914
EDR45810.1
KEGG: lsl:LSL_1714 4.9e-75 PTS system, mannose-specific IID component K00890; COG: COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.913
EDR45811.1
KEGG: lsl:LSL_1715 3.4e-67 PTS system, mannose-specific IIC component K00890; COG: COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.909
hprK
HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...]
 
   
 0.844
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
  
  
 0.819
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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