Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EDR47654.15'-nucleotidase, C-terminal domain protein; KEGG: afu:AF0876 6.5e-57 nt5; 5'-nucleotidase (nt5) K01081; COG: COG0737 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. (651 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.730
add
Adenosine deaminase; KEGG: efa:EF0171 6.3e-59 add; adenosine deaminase K01488; COG: COG1816 Adenosine deaminase; Psort location: Cytoplasmic, score: 8.87.
    
 0.572
deoD
KEGG: bcl:ABC4021 8.9e-76 deoD; purine-nucleoside phosphorylase K03784; COG: COG0813 Purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 8.87.
    
 0.556
EDR46484.1
Cna protein B-type domain protein; KEGG: ddi:DDB0191487 0.00014 kinX; LISK family protein kinase K05743; COG: COG4932 Predicted outer membrane protein; Psort location: Cellwall, score: 9.26.
  
   
 0.447
EDR48183.1
Hydrolase, alpha/beta domain protein; KEGG: fal:FRAAL0236 9.9e-17 putative esterase K01066; COG: COG0657 Esterase/lipase; Psort location: Cytoplasmic, score: 8.87.
 
 
   0.439
EDR45598.1
Hypothetical protein; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Psort location: Cytoplasmic, score: 8.87.
  
   
 0.439
EDR48181.1
Hydrolase, alpha/beta domain protein; KEGG: bcz:BCZK0735 2.9e-20 lipW; possible esterase K01066; COG: COG0657 Esterase/lipase; Psort location: Cytoplasmic, score: 9.98.
 
 
   0.419
EDR48434.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: btl:BALH_0703 2.0e-140 ndh; NADH dehydrogenase K00356; COG: COG0607 Rhodanese-related sulfurtransferase; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.400
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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