STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR47279.1Putative cob(I)yrinic acid a,c-diamide adenosyltransferase; KEGG: cpr:CPR_1875 1.4e-31 cob(I)alamin adenosyltransferase, putative K00798; COG: COG2109 ATP:corrinoid adenosyltransferase; Psort location: Cytoplasmic, score: 9.98. (174 aa)    
Predicted Functional Partners:
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.994
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.957
cobS
Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.957
cobB
KEGG: lin:lin1154 2.8e-79 cbiA; similar to cobyrinic acid a,c-diamide synthase K03401; COG: COG1797 Cobyrinic acid a,c-diamide synthase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.953
EDR45705.1
Hypothetical protein; KEGG: tde:TDE2382 1.1e-13 cobU; cobinamide kinase/cobinamide phosphate guanyltransferase K02231; COG: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.927
EDR45703.1
Hypothetical protein; KEGG: cno:NT01CX_2078 3.1e-12 cobinamide kinase; COG: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.916
cobK
precorrin-6A reductase; KEGG: ctc:CTC00734 4.6e-56 cbiT; precorrin-6B methylase/decarboxylase cbiT/cbiE K03399:K02191; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.761
nth
Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.742
EDR47280.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.732
cobA
uroporphyrinogen-III C-methyltransferase; KEGG: cno:NT01CX_0261 1.5e-89 uroporphyrinogen III synthase/methyltransferase K00589; COG: COG1587 Uroporphyrinogen-III synthase; Psort location: Cytoplasmic, score: 8.87.
    
 0.725
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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