STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR47282.12-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 2.6e-117 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. (382 aa)    
Predicted Functional Partners:
EDR48408.1
Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 5.7e-42 yjiL; hypothetical protein YjiL K04111; COG: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); Psort location: Cytoplasmic, score: 8.87.
 0.987
EDR46948.1
Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 4.7e-19 yjiL; hypothetical protein YjiL K04111; COG: COG3580 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
  
 0.659
EDR47280.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.483
nth
Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.483
EDR47279.1
Putative cob(I)yrinic acid a,c-diamide adenosyltransferase; KEGG: cpr:CPR_1875 1.4e-31 cob(I)alamin adenosyltransferase, putative K00798; COG: COG2109 ATP:corrinoid adenosyltransferase; Psort location: Cytoplasmic, score: 9.98.
       0.460
yedF
Selenium metabolism protein YedF; COG: NOG13230 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87; Belongs to the sulfur carrier protein TusA family.
 
    0.460
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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