Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDR47296.1Putative permease; KEGG: bcz:BCZK0244 3.5e-97 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; COG: COG2252 Permeases; Psort location: CytoplasmicMembrane, score: 9.99. (460 aa)    
Predicted Functional Partners:
EDR47701.1
Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.867
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
    0.581
EDR47902.1
Putative permease; KEGG: bcz:BCZK0244 4.4e-05 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; COG: COG2233 Xanthine/uracil permeases; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.572
purD
KEGG: dps:DP2188 1.5e-114 probable phosphoribosylamine--glycine ligase K01945; COG: COG0151 Phosphoribosylamine-glycine ligase; Psort location: Cytoplasmic, score: 8.87; Belongs to the GARS family.
  
  
 0.557
EDR47182.1
Putative permease; KEGG: art:Arth_3333 0.0019 carbonate dehydratase K01672; COG: COG2233 Xanthine/uracil permeases; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.531
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
  
 0.526
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: gka:GK0265 2.3e-102 phosphoribosylaminoimidazole synthetase K01933; COG: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.515
EDR45943.1
AICARFT/IMPCHase bienzyme; KEGG: dme:Dmel_CG11089 3.3e-124 CG11089 K00602:K01492; COG: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Psort location: Cytoplasmic, score: 8.87.
  
  
 0.514
purC
KEGG: gsu:GSU2091 1.0e-83 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; COG: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the SAICAR synthetase family.
  
  
 0.510
EDR46503.1
KEGG: mle:ML2279 1.9e-05 putative transmembrane transport protein K01672; COG: COG2233 Xanthine/uracil permeases; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.499
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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