STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nifUFe-S iron-sulfur cluster assembly protein, NifU family; KEGG: rxy:Rxyl_1354 1.2e-20 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566; COG: COG0822 NifU homolog involved in Fe-S cluster formation; Psort location: Cytoplasmic, score: 8.87. (147 aa)    
Predicted Functional Partners:
nifS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
 0.999
EDR47844.1
Aminotransferase, class V; KEGG: tte:TTE1663 1.2e-105 nifS; Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes K04487; COG: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Psort location: Cytoplasmic, score: 8.87.
 
 0.998
EDR47398.1
Cysteine desulfurase family protein; KEGG: mta:Moth_2214 4.9e-84 cysteine desulphurase related, unknown function K01763; COG: COG0520 Selenocysteine lyase; Psort location: Cytoplasmic, score: 8.87.
  
 0.994
EDR47489.1
Selenium-dependent molybdenum hydroxylase system protein, YqeB family; COG: COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family; Psort location: Cytoplasmic, score: 8.87.
  
 0.963
EDR46544.1
SufB/sufD domain protein; COG: COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.919
EDR46543.1
Putative FeS assembly ATPase SufC; KEGG: ctc:CTC01702 7.3e-26 ABC-transporter ATP-binding protein, iron(III) K02010; COG: COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
  
  
 0.882
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
  
 0.837
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 
 0.813
EDR46936.1
Transcriptional regulator, Rrf2 family; KEGG: ama:AM656 1.2e-08 aminotransferase, class V K04487; COG: COG1959 Predicted transcriptional regulator; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.802
EDR46654.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.788
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.