STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR46952.1Sugar-specific transcriptional regulator, TrmB family; COG: COG1378 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87. (243 aa)    
Predicted Functional Partners:
EDR46953.1
KEGG: spn:SP_1978 2.1e-145 diaminopimelate decarboxylase K01586; COG: COG0019 Diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 8.87.
 
     0.846
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
    0.759
EDR46752.1
COG: COG1715 Restriction endonuclease; Psort location: Cytoplasmic, score: 8.87.
   
    0.759
EDR46950.1
Hypothetical protein; KEGG: mmu:246104 0.0091 Rhbdl3; rhomboid, veinlet-like 3 (Drosophila); COG: COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.555
EDR47153.1
4Fe-4S binding domain protein; KEGG: ecp:ECP_0909 5.0e-27 anaerobic dimethyl sulfoxide reductase, subunit B K07307; COG: COG0437 Fe-S-cluster-containing hydrogenase components 1; Psort location: CytoplasmicMembrane, score: 9.49.
   
    0.514
EDR45683.1
4Fe-4S binding domain protein; KEGG: ecp:ECP_0909 5.9e-24 anaerobic dimethyl sulfoxide reductase, subunit B K07307; COG: COG0437 Fe-S-cluster-containing hydrogenase components 1; Psort location: CytoplasmicMembrane, score: 9.49.
   
    0.514
pyk
Pyruvate kinase; KEGG: tte:TTE1815 2.8e-136 pykF; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
     
 0.485
EDR46203.1
Hypothetical protein; COG: KOG3704 Heparan sulfate D-glucosaminyl 3-O-sulfotransferase; Psort location: CytoplasmicMembrane, score: 7.63.
  
     0.412
EDR46954.1
Purine catabolism regulatory protein-like family; COG: COG2508 Regulator of polyketide synthase expression; Psort location: Cytoplasmic, score: 8.87.
       0.410
EDR46702.1
Hypothetical protein; COG: NOG09581 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.401
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.