STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflBKEGG: bli:BL01863 3.6e-269 hypothetical formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98. (769 aa)    
Predicted Functional Partners:
pflA
Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
 0.972
nifJ
KEGG: ctc:CTC01741 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
    
 0.952
pta
Phosphate acetyltransferase; KEGG: hhe:HH1309 1.8e-100 pta; phosphotransacetylase K00625; COG: COG0280 Phosphotransacetylase; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.915
EDR47352.1
Aldehyde dehydrogenase (NAD) family protein; KEGG: cpe:CPE2531 0. adhE; alcohol dehydrogenase / acetaldehyde dehydrogenase K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
 
 0.913
EDR47540.1
Glycyl-radical enzyme activating protein family protein; KEGG: cno:NT01CX_0497 3.9e-59 pflC; pyruvate formate-lyase K00538; COG: COG1180 Pyruvate-formate lyase-activating enzyme; Psort location: Cytoplasmic, score: 9.98.
 
  
 0.903
EDR48332.1
2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family; KEGG: cno:NT01CX_0147 5.6e-67 porG; pyruvate synthase subunit PorC K00168; COG: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; Psort location: Cytoplasmic, score: 8.87.
     
 0.887
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
 
 0.836
EDR45865.1
Malic enzyme, NAD binding domain protein; KEGG: tte:TTE2332 3.2e-126 sfcA; malic enzyme K00027; COG: COG0281 Malic enzyme; Psort location: CytoplasmicMembrane, score: 9.76.
   
 
 0.823
EDR48334.1
Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; KEGG: ctc:CTC02526 2.0e-126 porA; pyruvate synthase subunit porA K00169; COG: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Psort location: Cytoplasmic, score: 8.87.
     
 0.821
EDR45358.1
Aldehyde dehydrogenase (NAD) family protein; KEGG: bca:BCE_1397 3.1e-121 ywdH; aldehyde dehydrogenase K00128; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.817
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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