Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
miaBtRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (470 aa)    
Predicted Functional Partners:
EDR47025.1
COG: COG4224 Uncharacterized protein conserved in bacteria.
       0.803
EDR47026.1
KEGG: pca:Pcar_2351 2.4e-27 5-formyltetrahydrofolate cyclo-ligase family protein K01934; COG: COG0212 5-formyltetrahydrofolate cyclo-ligase; Psort location: Cytoplasmic, score: 8.87.
       0.801
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
 0.799
EDR47027.1
Hypothetical protein; COG: NOG17973 non supervised orthologous group.
       0.783
rlmN-2
23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
 
  
 0.655
EDR47024.1
Hypothetical protein.
       0.601
EDR47029.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.26.
       0.560
ybeY
Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
    0.524
sun
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.515
rlmN
23S rRNA m2A2503 methyltransferase; KEGG: fnu:FN0127 0.0029 Fe-S oxidoreductase; COG: COG0820 Predicted Fe-S-cluster redox enzyme; Psort location: Cytoplasmic, score: 8.87; Belongs to the radical SAM superfamily. RlmN family.
 
  
 0.496
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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