Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
EDR47034.1Flavoprotein family protein; KEGG: gox:GOX1717 3.8e-16 putative oxidoreductase K00100; COG: COG2081 Predicted flavoproteins; Psort location: Cytoplasmic, score: 8.87. (412 aa)    
Predicted Functional Partners:
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
       0.763
EDR47033.1
Aluminum resistance protein; KEGG: ava:Ava_4213 3.2e-103 Cys/Met metabolism pyridoxal-phosphate-dependent enzyme K01758; COG: COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance; Psort location: Cytoplasmic, score: 8.87.
       0.763
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
       0.682
mutL
DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
       0.682
EDR47035.1
Response regulator receiver domain protein; KEGG: ava:Ava_2028 1.0e-13 two component transcriptional regulator, LuxR family; COG: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
       0.595
EDR47036.1
HAMP domain protein; KEGG: bli:BL01744 5.2e-48 histidine kinase,histidine kinase, HAMP region; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; Psort location: CytoplasmicMembrane, score: 9.98.
       0.594
EDR47037.1
ABC transporter, solute-binding protein; COG: COG1653 ABC-type sugar transport system, periplasmic component.
       0.594
EDR47043.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: gox:GOX1630 1.4e-68 putative oxidoreductase K00100; COG: COG2509 Uncharacterized FAD-dependent dehydrogenases.
 
     0.457
miaB
tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
       0.424
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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