Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
radCCOG: COG2003 DNA repair proteins; Psort location: Cytoplasmic, score: 8.87; Belongs to the UPF0758 family. (230 aa)    
Predicted Functional Partners:
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.959
maf
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
 
  
 0.876
EDR47046.1
Cell shape determining protein, MreB/Mrl family; KEGG: hpa:HPAG1_1318 8.1e-43 rod shape-determining protein K01529; COG: COG1077 Actin-like ATPase involved in cell morphogenesis; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.835
mreD
Rod shape-determining protein MreD; COG: NOG16883 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.814
EDR47049.1
Penicillin-binding protein, transpeptidase domain protein; KEGG: sde:Sde_3341 9.2e-54 PAS/PAC sensor signal transduction histidine kinase K05364; COG: COG0768 Cell division protein FtsI/penicillin-binding protein 2; Psort location: CytoplasmicMembrane, score: 9.82.
       0.785
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
   
 0.706
EDR47044.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.75.
       0.703
mutL
DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.661
EDR48459.1
comF family protein; KEGG: reh:H16_A0339 6.5e-18 predicted amidophosphoribosyltransferase; COG: COG1040 Predicted amidophosphoribosyltransferases; Psort location: Cytoplasmic, score: 8.87.
 
    0.657
dprA
DNA protecting protein DprA; COG: COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.602
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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