STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR47068.1LysM domain protein; KEGG: lmf:LMOf2365_2670 3.9e-05 autolysin K01446; Psort location: Cytoplasmic, score: 8.87. (129 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
    
 0.788
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.771
xseB
Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
     0.748
EDR48411.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.744
EDR48283.1
Competence/damage-inducible domain protein CinA; COG: COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Psort location: Cytoplasmic, score: 8.87; Belongs to the CinA family.
   
 
  0.741
EDR48294.1
Hypothetical protein; COG: COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Psort location: Cytoplasmic, score: 8.87; Belongs to the CinA family.
   
 
  0.741
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
  
 0.740
EDR48260.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.734
EDR47784.1
Hypothetical protein.
  
     0.725
EDR47982.1
Hypothetical protein; KEGG: cal:orf19.6369 0.0066 RIO2; RIO-like serine/threonine protein kinase K07179; COG: COG3906 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
  
     0.714
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.