STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR47082.1HAD hydrolase, family IA, variant 3; KEGG: atc:AGR_C_1458 2.0e-14 conserved hypothetical protein VC1645 K01560; COG: COG1011 Predicted hydrolase (HAD superfamily); Psort location: Cytoplasmic, score: 8.87. (202 aa)    
Predicted Functional Partners:
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.845
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.822
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
    
  0.794
EDR48306.1
Hypothetical protein; KEGG: cpr:CPR_1841 1.2e-128 phosphomannomutase K01840; COG: COG1109 Phosphomannomutase; Psort location: Cytoplasmic, score: 8.87.
  
 
  0.781
EDR46537.1
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
   
 
  0.778
EDR48283.1
Competence/damage-inducible domain protein CinA; COG: COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Psort location: Cytoplasmic, score: 8.87; Belongs to the CinA family.
    
  0.771
EDR48294.1
Hypothetical protein; COG: COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Psort location: Cytoplasmic, score: 8.87; Belongs to the CinA family.
    
  0.771
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
  
 
  0.762
EDR48215.1
ROK family protein; KEGG: spa:M6_Spy0250 1.6e-92 N-acetylmannosamine kinase K00885; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 9.98.
   
 
  0.736
EDR48054.1
ROK family protein; KEGG: cac:CAC2613 5.8e-88 glcK; transcriptional regulators of NagC/XylR family K00845; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 9.98.
   
 
  0.736
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.