Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR47099.1KEGG: nwi:Nwi_0477 5.4e-30 short-chain dehydrogenase/reductase SDR; COG: COG0300 Short-chain dehydrogenases of various substrate specificities; Psort location: Cytoplasmic, score: 8.87; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (253 aa)    
Predicted Functional Partners:
EDR47097.1
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.819
recU
Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
       0.796
EDR47098.1
Hypothetical protein.
       0.785
EDR48060.1
AMP-binding enzyme; KEGG: bca:BCE_0965 4.7e-70 AMP-binding protein K01897; COG: COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; Psort location: Cytoplasmic, score: 9.98.
   
 
 0.736
EDR45604.1
AMP-binding enzyme; KEGG: bha:BH3104 1.2e-57 long-chain fatty-acid-CoA ligase K01897; COG: COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; Psort location: CytoplasmicMembrane, score: 9.49.
   
 
 0.736
EDR45606.1
AMP-binding enzyme; KEGG: afu:AF1772 3.3e-53 fadD-7; long-chain-fatty-acid--CoA ligase (FadD-7) K01897; COG: COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; Psort location: CytoplasmicMembrane, score: 9.49.
   
 
 0.736
EDR47102.1
NOL1/NOP2/sun family protein; KEGG: lsl:LSL_0999 1.5e-71 putative 23S rRNA m(5)C methyltransferase K00599; COG: COG3270 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
       0.649
EDR47100.1
Putative radical SAM protein YgiQ; KEGG: fnu:FN0734 2.1e-131 Fe-S oxidoreductase; COG: COG1032 Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87.
  
    0.648
EDR47101.1
Pseudouridylate synthase; KEGG: tte:TTE0052 2.4e-66 rsuA; 16S rRNA uridine-516 pseudouridylate synthase and related Pseudouridylate synthase K06183; COG: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Psort location: Cytoplasmic, score: 8.87; Belongs to the pseudouridine synthase RsuA family.
       0.617
EDR46355.1
K+-dependent Na+/Ca+ exchanger family protein; COG: COG0530 Ca2+/Na+ antiporter; Psort location: CytoplasmicMembrane, score: 9.99.
    
   0.588
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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