STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepDXaa-His dipeptidase; KEGG: cpr:CPR_2216 2.9e-118 pepD; aminoacyl-histidine dipeptidase K01270; COG: COG2195 Di- and tripeptidases; Psort location: Cytoplasmic, score: 8.87. (500 aa)    
Predicted Functional Partners:
EDR45850.1
Aminotransferase, class I/II; KEGG: cac:CAC2832 5.0e-114 PLP-dependent aminotransferase K00811; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score: 8.87.
   
  0.866
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.813
glyA-2
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.813
EDR47526.1
Aminotransferase, class I/II; KEGG: tte:TTE2440 4.1e-126 avtA4; PLP-dependent aminotransferases K00821; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score: 8.87.
   
  0.791
patB
Cystathionine beta-lyase PatB; KEGG: oih:OB2338 1.1e-70 aminotransferase K00842; COG: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.
    
  0.743
EDR46623.1
Aminotransferase, class I/II; KEGG: ctc:CTC00825 5.6e-67 putative aspartate aminotransferase K00842; COG: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; Psort location: Cytoplasmic, score: 8.87.
    
  0.743
EDR45853.1
Aminotransferase, class I/II; KEGG: cac:CAC2970 8.8e-101 patB; PLP-dependent aminotransferase, K00842; COG: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; Psort location: Cytoplasmic, score: 8.87.
    
  0.743
EDR47105.1
Putative sporulation integral membrane protein YlbJ; COG: COG3314 Uncharacterized protein conserved in bacteria; Psort location: CytoplasmicMembrane, score: 9.99.
       0.562
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.532
EDR48572.1
Creatinase; KEGG: bfs:BF4027 3.7e-125 putative peptidase K01262; COG: COG0006 Xaa-Pro aminopeptidase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.528
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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