STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (676 aa)    
Predicted Functional Partners:
EDR47111.1
DAK2 domain fusion protein YloV; KEGG: bcz:BCZK3615 7.4e-120 dhaK; possible dihydroxyacetone-related kinase K00863; COG: COG1461 Predicted kinase related to dihydroxyacetone kinase; Psort location: Cytoplasmic, score: 8.87.
  
    0.855
EDR48147.1
Hypothetical protein; KEGG: cgl:NCgl0024 3.8e-16 cgl0025; predicted transcriptional regulator K01529; COG: COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen; Psort location: Cytoplasmic, score: 8.87.
   
 
  0.837
EDR47112.1
COG: COG1302 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
       0.799
EDR46756.1
Hypothetical protein; KEGG: mma:MM0198 4.7e-25 ATP-dependent DNA helicase K01529; COG: COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen; Psort location: Cytoplasmic, score: 8.87.
   
 
  0.730
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.716
EDR47109.1
Small, acid-soluble spore protein, alpha/beta type; COG: NOG16862 non supervised orthologous group.
       0.682
dprA
DNA protecting protein DprA; COG: COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; Psort location: Cytoplasmic, score: 8.87.
  
     0.603
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.571
EDR47113.1
Hypothetical protein.
       0.537
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
  
   
 0.525
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.