| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDR47147.1 | EDR47148.1 | DORFOR_01638 | DORFOR_01639 | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 1.5e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | DNA topoisomerase; KEGG: cac:CAC3567 6.1e-93 topB; topoisomerase B K03169; COG: COG0550 Topoisomerase IA; Psort location: Cytoplasmic, score: 8.87. | 0.617 |
| EDR47147.1 | glmM | DORFOR_01638 | DORFOR_02539 | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 1.5e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.936 |
| EDR47147.1 | glmS | DORFOR_01638 | DORFOR_03289 | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 1.5e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.604 |
| EDR47147.1 | nadE | DORFOR_01638 | DORFOR_00816 | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 1.5e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.500 |
| EDR47147.1 | ppk1 | DORFOR_01638 | DORFOR_01640 | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 1.5e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.459 |
| EDR47147.1 | prs | DORFOR_01638 | DORFOR_00599 | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 1.5e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | Ribose-phosphate diphosphokinase; KEGG: cac:CAC0819 9.8e-102 phosphoribosylpyrophosphate synthetase K00948; COG: COG0462 Phosphoribosylpyrophosphate synthetase; Psort location: CytoplasmicMembrane, score: 7.80; Belongs to the ribose-phosphate pyrophosphokinase family. | 0.670 |
| EDR47147.1 | prs-2 | DORFOR_01638 | DORFOR_02870 | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 1.5e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | KEGG: cpr:CPR_1519 1.9e-98 prs; ribose-phosphate pyrophosphokinase K00948; COG: COG0462 Phosphoribosylpyrophosphate synthetase; Psort location: Cytoplasmic, score: 8.87. | 0.671 |
| EDR47147.1 | rfbA | DORFOR_01638 | DORFOR_00945 | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 1.5e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 0.785 |
| EDR47147.1 | secD | DORFOR_01638 | DORFOR_00851 | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 1.5e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.484 |
| EDR47147.1 | thyA | DORFOR_01638 | DORFOR_00834 | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 1.5e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.509 |
| EDR47148.1 | EDR47147.1 | DORFOR_01639 | DORFOR_01638 | DNA topoisomerase; KEGG: cac:CAC3567 6.1e-93 topB; topoisomerase B K03169; COG: COG0550 Topoisomerase IA; Psort location: Cytoplasmic, score: 8.87. | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 1.5e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | 0.617 |
| EDR47148.1 | ppk1 | DORFOR_01639 | DORFOR_01640 | DNA topoisomerase; KEGG: cac:CAC3567 6.1e-93 topB; topoisomerase B K03169; COG: COG0550 Topoisomerase IA; Psort location: Cytoplasmic, score: 8.87. | Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.544 |
| EDR47148.1 | secD | DORFOR_01639 | DORFOR_00851 | DNA topoisomerase; KEGG: cac:CAC3567 6.1e-93 topB; topoisomerase B K03169; COG: COG0550 Topoisomerase IA; Psort location: Cytoplasmic, score: 8.87. | Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.523 |
| glmM | EDR47147.1 | DORFOR_02539 | DORFOR_01638 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 1.5e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | 0.936 |
| glmM | glmS | DORFOR_02539 | DORFOR_03289 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.951 |
| glmS | EDR47147.1 | DORFOR_03289 | DORFOR_01638 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 1.5e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | 0.604 |
| glmS | glmM | DORFOR_03289 | DORFOR_02539 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.951 |
| glmS | nadE | DORFOR_03289 | DORFOR_00816 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.492 |
| nadE | EDR47147.1 | DORFOR_00816 | DORFOR_01638 | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 1.5e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | 0.500 |
| nadE | glmS | DORFOR_00816 | DORFOR_03289 | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.492 |