STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR47165.1Bacterial peptidase A24, N-terminal domain protein; KEGG: ppd:Ppro_0982 1.4e-36 prepilin peptidase; COG: COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; Psort location: CytoplasmicMembrane, score: 10.00. (260 aa)    
Predicted Functional Partners:
EDR47166.1
Hypothetical protein.
       0.723
EDR47167.1
Hypothetical protein.
       0.689
EDR45858.1
Hypothetical protein.
  
  
 0.613
dprA
DNA protecting protein DprA; COG: COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.611
EDR45880.1
comEA protein; COG: COG1555 DNA uptake protein and related DNA-binding proteins; Psort location: CytoplasmicMembrane, score: 9.49.
   
  
 0.594
EDR45876.1
DNA internalization competence protein ComEC/Rec2-like protein; COG: COG0658 Predicted membrane metal-binding protein; Psort location: CytoplasmicMembrane, score: 9.97.
  
  
 0.534
EDR48144.1
COG: COG4969 Tfp pilus assembly protein, major pilin PilA.
 
   
 0.476
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
    0.474
EDR45514.1
Hypothetical protein; COG: COG1943 Transposase and inactivated derivatives; Psort location: Cytoplasmic, score: 8.87.
 
     0.439
EDR47913.1
Metallo-beta-lactamase domain protein; KEGG: nmu:Nmul_A1621 0.0028 hydroxyacylglutathione hydrolase K01069; COG: COG2247 Putative cell wall-binding domain.
 
  
 0.438
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (34%) [HD]