STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lepBSignal peptidase I; KEGG: mta:Moth_0972 1.2e-34 peptidase S26A, signal peptidase I K03100; COG: COG0681 Signal peptidase I; Psort location: CytoplasmicMembrane, score: 9.82. (186 aa)    
Predicted Functional Partners:
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.667
EDR47182.1
Putative permease; KEGG: art:Arth_3333 0.0019 carbonate dehydratase K01672; COG: COG2233 Xanthine/uracil permeases; Psort location: CytoplasmicMembrane, score: 10.00.
       0.631
EDR46243.1
KEGG: ctc:CTC02332 8.6e-39 V-type sodium ATP synthase subunit C K02119; COG: COG1527 Archaeal/vacuolar-type H+-ATPase subunit C; Psort location: Cytoplasmic, score: 8.87.
     
  0.627
secD
Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
  
 0.565
EDR47184.1
Hypothetical protein.
       0.561
EDR47051.1
Putative cell division topological specificity factor MinE; Psort location: Cytoplasmic, score: 8.87.
   
    0.542
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.541
EDR46246.1
KEGG: mth:MTH956 6.4e-11 ATP synthase, subunit F K02122; COG: COG1436 Archaeal/vacuolar-type H+-ATPase subunit F; Psort location: Cytoplasmic, score: 8.87.
   
 
  0.532
rseP
RIP metalloprotease RseP; KEGG: cac:CAC1796 6.3e-59 predicted membrane-associated Zn-dependent protease; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.464
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
  
 0.461
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (34%) [HD]