Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EDR47188.1Conserved hypothetical protein, YfiH family; COG: COG1496 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87; Belongs to the multicopper oxidase YfiH/RL5 family. (278 aa)    
Predicted Functional Partners:
EDR47058.1
Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.842
EDR47189.1
TIGR00252 family protein; KEGG: sat:SYN_00772 9.9e-22 endonuclease; COG: COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Psort location: Cytoplasmic, score: 8.87; Belongs to the UPF0102 family.
       0.658
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.658
lepB-2
KEGG: cac:CAC1760 4.2e-30 signal peptidase I K03100; COG: COG0681 Signal peptidase I; Psort location: CytoplasmicMembrane, score: 9.82; Belongs to the peptidase S26 family.
  
    0.640
EDR47187.1
COG: COG0668 Small-conductance mechanosensitive channel; Psort location: CytoplasmicMembrane, score: 9.99.
       0.633
ylqF
Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
       0.596
lepB-3
Signal peptidase I; KEGG: ctc:CTC01253 3.7e-22 putative signal peptidase I K03100; COG: COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
 
     0.587
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
       0.430
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
   
 0.403
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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